Welcome to IMPI’s documentation!¶
Our Interface for Point Mutation Identification (IMPI) is a stand-alone software and implements algoirthms which allow for unique molecular identifier (UMI) tagged next-generation sequencing (NGS) data processing and the analysis of minor and variant allele frequencies (MAF and VAF), respectively.
The software is developed by researchers of the Bioinformatics Research Group at FH Upper Austria, Hagenberg Campus and researchers of the Laboratory for Molecular Genetic Diagnostics at the Ordensklinikum Linz GmbH, Barmherzige Schwestern.
- Configuration settings
- Pre-processing methods
- Allele frequency analysis
- Module: UMI-tools analysis
- Module: Parameter optimization
- Module: Wild-type correction
- Module: Cross-sample contamination analysis
- Output summaries
- Usage from command line