ProComCure In Silico Validation
|Head||DI (FH) Thomas Kern|
|Researchers||Dipl.-Ing. (FH) Wolfgang Straßer|
|Duration||2005 - 2008|
|Research focus||Software technology and application|
|Research institutions||University of Applied Sciences, Upper Austria, Hagenberg Campus |
Research Center Hagenberg
|Project description|| |
Procomcure targets heterologous protein-protein interactions in host-pathogen interactions, specifically infections caused by multi-drug resistant Staphylococcus aureus. This limited-spectrum approach focusing on severe diseases considers the role of the host in acquisition and dissemination of infections and development of resistance.
Procomcure uses a method that exploits qualified host-pathogen protein-protein interactions, using peptides derived from interacting partners, selected for tight binding, as lead structures for new chemical entities.