ProComCure In Silico Validation

Head DI (FH) Thomas Kern
Researchers Dipl.-Ing. (FH) Wolfgang Stra├čer
Duration 2005 - 2008
Research focus Software technology and application 
Research institutions University of Applied Sciences, Upper Austria, Hagenberg Campus
Research Center Hagenberg
Project description

Procomcure targets heterologous protein-protein interactions in host-pathogen interactions, specifically infections caused by multi-drug resistant Staphylococcus aureus. This limited-spectrum approach focusing on severe diseases considers the role of the host in acquisition and dissemination of infections and development of resistance.

Procomcure uses a method that exploits qualified host-pathogen protein-protein interactions, using peptides derived from interacting partners, selected for tight binding, as lead structures for new chemical entities.