Head DI (FH) Thomas Kern 
Researchers Mag. Karin Breuer
Dipl.-Ing. (FH) Christian Frech
Duration 2005 - 2006
Research focus Software technology and application 
Research institutions University of Applied Sciences, Upper Austria, Hagenberg Campus
Research Center Hagenberg
Project description

Molecular Biological Screening Assay for Gynaecological Smear Diagnostic in Routine Laboratories.

Recent molecular biological screening methods are only applicable for singular micro-organisms or viruses. Especially for clinical gynaecology, such methods are not only time-intense and expensive, but also unreliable. Moreover, there are up to 200 relevant germs, each one needing an own test. Therefore, an integrated multianalyte assay shall be designed to replace this vast amount of different tests.

A fast and accurate screening method would improve medical diagnostics significantly and augment preventive woman medicine drastically. The objective of this project is the realization of such a screening. All potentially harmful micro-organisms and viruses of the vaginal milieu will be quantitatively measured and analyzed. In parallel, preneoplastic leasions can be characterized on a molecular level. This multi-analyte assay will be used for acute and preventive strategies. For the first time a routine diagnostics tool will be available, which gives the gynaecologist a complete picture of microbial and viral status.

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