Projects

MS Amanda

Head DI(FH) Viktoria Dorfer MSc
Researchers

DI(FH) Viktoria Dorfer MSc
Sebastian Dorl MSc
Prof.(FH) DI Dr. Stephan Winkler

Duration 2011 - present
Research focus Software technology and application 
Research institutions University of Applied Sciences, Upper Austria, Hagenberg Campus
Research Center Hagenberg
Project description

The development of the peptide and protein identification algorithm MS Amanda has been started within this project; this scoring system is developed by the Bioinformatics Research Group in close cooperation with the group of Karl Mechtler at IMP Vienna and especially focused on the identification of peptides and proteins of tandem mass spectrometry data.

It is motivated by the fact that only 30-50 % of the spectra of a mass spectrometry run can be satisfyingly interpreted due to various reasons, including – often unknown – posttranslational modifications. In addition, the algorithms used by the majority of the proteomics community have been developed more than 10 years ago and do not provide sufficient results for high resolution tandem mass spectrometers which only emerged recently. 

The implementation of MS Amanda for Proteome Discoverer 1.3 and 1.4 can be found online: ms.imp.ac.at

Additional material Download MS Amanda for PD 1.3.0.339
Download MS Amanda for PD 1.4.0.288
Download MS Amanda Poster